Season 1
A fire leads investigators to re-examine an unusual death, which meant digging up the victim who had been buried for years.
The body of a young woman is discovered in a remote area, leading forensic investigators on a search for clues to identify her and her killer.
When a Yale student mysteriously vanishes days before her wedding, investigators comb a secure research lab for evidence.
Police make a shocking discovery when they open a suitcase found floating in a bay.
Investigators gather forensic clues to find out what happened to a popular New Hampshire handyman.
A woman is killed in a crowded parking lot in the middle of the day. It looks like a professional hit, but evidence unveils an elaborate plan.
Police race to find a serial killer terrorizing a small Texas town.
Cell phone forensics help investigators solve a murder in an upscale community.
After a young couple is killed on a road trip, their families began receiving disturbing letters.
After a young mom is found murdered in her home, investigators find startling clues on her cell phone that could lead to her killer.
Investigators think they know who killed a young woman, but new forensic technology turns the case upside down.
A small community is shocked when a woman is shot and killed in a church. Police are left with few pieces of evidence and no suspects.
An insurance agent is shot in his office in broad daylight, but police struggle to find any fingerprints or the murder weapon.
A healthy, young mother mysteriously dies after a minor traffic accident — triggering an investigation to find out what caused her death.
Investigators search for clues after a body is discovered in a Florida waterway.
Season 2
As rumors spread through a small town about who murdered a teacher's aide, the real killer gets further away. A scientific breakthrough cracks the case.
A man is found dead with the letters "F E D" written on his chest. With little other evidence, police turn to the cryptic marking for answers.
When a single mom disappears, homicide detectives look into men she matched with on dating sites, men from work and a lover with a violent past.
A 20-year-old woman goes for a bike ride and never returns. Years go by without any evidence or leads until new technology breaks the case.
A navy lieutenant's death is ruled as arsenic poisoning. Investigators discover he had many enemies, but it takes years to uncover what really happened.
A building manager finds a woman dead in the bathtub. When questioned, the neighbor living downstairs lies to police.
Forensic experts piece together strange clues and microscopic evidence to solve a puzzling case — proving there is no such thing as a perfect crime.
A husband wants a divorce, and his wife ends up murdered. But he has an airtight alibi. Police use forensic science to come to an unexpected conclusion.
When a woman is shot in the suburbs of Michigan, surveillance video reveals it was a trio of killers. A handwritten note becomes a critical clue.
A serial killer is on the loose for two decades. Finally, an arrest is made and police discover someone unexpected is behind the years of crime.
Detectives are determined to do whatever it takes to catch a criminally charged sex offender and murderer. They use a crucial piece of evidence: a palm print.
A house fire kills the only doctor in a small town. An arson investigation points to the son of the doctor's nurse.
The case of a young woman who was murdered in Wisconsin remains unsolved for nearly three decades. Forensics from an unrelated crime provide new details.
An elderly man is shot and killed on a road trip. Random murders are among the hardest to solve, but ballistics give investigators an edge.
Season 3
An explosion that killed a California farmhand was eventually linked to a bomb. Looking for a motive, investigators hear ominous rumors about a jealous rage.
When a 79-year-old woman is found shot to death in her home, investigators initially suspect her husband or a violent neighbor. Shell casings recovered at the scene and a high-tech database reveal the unlikely killer.
A young single mother is abducted from a gas station and later found stabbed to death near an oil field. Detectives use shoe and tire impressions to weed out numerous suspects and find their killer.
When a 23-year-old Marine dies in his bedroom, doctors initially believe a heart attack is to blame, but when arsenic is found in his organs, his wife is charged with murder. A sharp attorney and toxicological testing uncover the truth.
When an 18-year-old girl is abducted while talking on a pay phone, forensic evidence found on her clothing points police in the direction of a suspect who shockingly confesses that he didn't act alone.
The story of a kidnapping, ransom and murder ring in L.A. A pair of retired scientists use sonar equipment to locate the victims at the bottom of a reservoir.
Patients at the VA Hospital in Clarksburg, WV keep dying after experiencing shockingly low blood sugar levels. An investigation into their deaths reveals an overnight nurse was injecting patients with lethal doses of insulin.
A 70-year-old retired veteran is found dead on his boat after a bad sea storm. Detectives discover he was killed during an attempted robbery after winning $400 in Keno.
When a college student was stabbed in her apartment, suspicion fell on her roommate — until a bloody shoe print revealed the real killer.
Texas detectives raced to stop a killer targeting law enforcement. Finally, a single bullet casing uncovered the bizarre reason the killer wanted revenge.
When a young family was killed, investigators worked to decipher the threats spray painted on the walls of the crime scene.
A young woman was killed but her boyfriend escaped a gruesome attack. Nearly 50 years without an arrest, a new forensic test exposed a man with a dark secret.
After two workers were shot at a construction site, police zeroed in on one important clue — one of the killers stepped in dog feces.
A Texas ex-con was convicted for a murder he said he didn't commit. From behind bars, he was determined to use forensic science to prove his innocence.
Doctors couldn't figure out why a California woman kept getting sick. When she died, investigators found out someone had been lying.
The body of a 24-year-old criminology student was found wrapped in a blanket alongside a desolate road in Brooklyn, NY. Police discover the bouncer at a SoHo bar was her killer.